Sometimes after taking the first step (ingesting mifepristone), women experience regret and want to continue their pregnancy. If this happens, we can administer the abortion pill reversal protocol. There is hope! Over 4,000 pregnancies have been saved to date using abortion pill reversal.
It’s important to contact the Abortion Pill Rescue Network as soon as possible after taking mifepristone for the best chance of maintaining the pregnancy. There’s a 24/7 hotline to providers worldwide who offer reversal to women who have started a chemical abortion and are experiencing regret. We can help! You can call the national hotline or live chat with a medical professional on the website.
You may still be able to save your pregnancy
You can call the national hotline or live chat with a medical professional on the website
You may still be able to save your pregnancy
You can call the national hotline or live chat with a medical professional on the website
- 68% of pregnancies treated with oral progesterone were saved
- No apparent increase in birth defects
- Intramuscular progesterone and high dose oral progesterone as most effective, with reversal rates of 64% (P < 0.001) and 68% (P < 0.001), respectively
Sometimes women are afraid of the reversal causing birth defects, but evidence shows this is not a risk. The abortion pill reversal protocol is administered after ingesting the first drug, mifepristone. In children born after exposure to mifepristone, there have been no increased risks of birth defects shown. Abortion pill reversal is completed using oral progesterone. Natural progesterone has been used for over 50 years in the treatment of early pregnancies in women at risk of miscarriage. Progesterone is also used in women who have conceived with in vitro fertilization. There are no known increased risks of birth defects from ingesting natural progesterone.
From the time mifepristone is taken, there are about 72 hours when a woman can change her mind. However, it’s best to call within 24 hours. If you want to reverse the abortion, do not take the second medication, misoprostol. Misoprostol, if taken, is associated with birth defects.
Reviewed by Dr. John W., MD & Lynn B., RN, BSN
Footnotes
2. 2018 observational study: A case series detailing the successful reversal of the effects of mifepristone using progesterone: https://pubmed.ncbi.nlm.nih.gov/30831017/
https://www.guttmacher.org/article/2022/02/medication-abortion-now-accounts-more-half-all-us-abortions
Additional Resources
ASRM FACT SHEET http://www.reprodsurgery.org/uploadedFiles/ASRM_Content/News_and_Publications/Practice_Guidelines/Educational_Bulletins/Progesterone_supplementation.pdf
Baulieu.E.E.(1985)RU 486:an antprogestin steroid with contragestive activity in women. In Baulieu.E.E. and Segal,S>J.(eds),The Antprogestin Steroid RU 486 and Human Fertility Control. Plenum Press, New York
Delgado G, Davenport M. Progesterone Use to Reverse the Effects of Mifepristone. Ann Pharmacother 2012;46. Published Online, 27 Nov 2012, theannals.com, doi: 10.1345/aph.1R252
Bernard N, Elefant E, Carlier P, Tebacher M, Barjhoux C, Bos-Thompson M, Amar E, Descotes J, Vial T. Continuation of pregnancy after first-trimester exposure to mifepristone:and observational prospective study. BJOG 2013;120:568-575 http://onlinelibrary.wiley.com/doi/10.1111/1471-0528.12147/epdf
http:abortionpillreversal.com/page/2-Abortion%20Pill%20Reversal/
Davenport et. Al. publication pending.
Delgado G, Condly SJ, Davenport M, Tinnakornsrisuphap T, Mack J, Khauv V, Zhou PS. A case series detailing the successful reversal of the effects of mifepristone using progesterone. Issues Law Med. 2018 Spring;33(1):21-31. PMID: 30831017.
