Abortion Pill Reversal

Clearway Clinic
Patient Video
Medication abortion (also known as chemical abortion and abortion pills) currently accounts for just over 50% of abortions in the U.S. (1). This type of abortion is completed in 2 parts. The first part consists of taking mifepristone, a drug that blocks progesterone to the pregnancy. The second drug, misoprostol, is taken 24-48 hours later, causing the uterus to contract and expel the pregnancy.

Sometimes after taking the first step (ingesting mifepristone), women experience regret and want to continue their pregnancy. If this happens, we can administer the abortion pill reversal protocol. There is hope! Over 4,000 pregnancies have been saved to date using abortion pill reversal.

It’s important to contact the Abortion Pill Rescue Network as soon as possible after taking mifepristone for the best chance of maintaining the pregnancy. There’s a 24/7 hotline to providers worldwide who offer reversal to women who have started a chemical abortion and are experiencing regret. We can help! You can call the national hotline or live chat with a medical professional on the website.

Clearway Clinic
Abortion Reversal Video

You may still be able to save your pregnancy

You can call the national hotline or live chat with a medical professional on the website

You may still be able to save your pregnancy

You can call the national hotline or live chat with a medical professional on the website

Clearway Clinic
Abortion Reversal Video
Women are often told there’s no such thing as abortion pill reversal, but the statistics show otherwise. A 2018 peer-reviewed study was conducted on the use of supplemental progesterone to reverse the effects of mifepristone, with 754 patients being observed (2). This case study showed positive results, including:
  • 68% of pregnancies treated with oral progesterone were saved
  • No apparent increase in birth defects
  • Intramuscular progesterone and high dose oral progesterone as most effective, with reversal rates of 64% (P < 0.001) and 68% (P < 0.001), respectively

Sometimes women are afraid of the reversal causing birth defects, but evidence shows this is not a risk. The abortion pill reversal protocol is administered after ingesting the first drug, mifepristone. In children born after exposure to mifepristone, there have been no increased risks of birth defects shown. Abortion pill reversal is completed using oral progesterone. Natural progesterone has been used for over 50 years in the treatment of early pregnancies in women at risk of miscarriage. Progesterone is also used in women who have conceived with in vitro fertilization. There are no known increased risks of birth defects from ingesting natural progesterone.

From the time mifepristone is taken, there are about 72 hours when a woman can change her mind. However, it’s best to call within 24 hours. If you want to reverse the abortion, do not take the second medication, misoprostol. Misoprostol, if taken, is associated with birth defects.

Reviewed by Dr. John W., MD & Lynn B., RN, BSN


Additional Resources

ASRM FACT SHEET http://www.reprodsurgery.org/uploadedFiles/ASRM_Content/News_and_Publications/Practice_Guidelines/Educational_Bulletins/Progesterone_supplementation.pdf

Baulieu.E.E.(1985)RU 486:an antprogestin steroid with contragestive activity in women. In Baulieu.E.E. and Segal,S>J.(eds),The Antprogestin Steroid RU 486 and Human Fertility Control. Plenum Press, New York

Delgado G, Davenport M. Progesterone Use to Reverse the Effects of Mifepristone. Ann Pharmacother 2012;46. Published Online, 27 Nov 2012, theannals.com, doi: 10.1345/aph.1R252

Bernard N, Elefant E, Carlier P, Tebacher M, Barjhoux C, Bos-Thompson M, Amar E, Descotes J, Vial T. Continuation of pregnancy after first-trimester exposure to mifepristone:and observational prospective study. BJOG 2013;120:568-575 http://onlinelibrary.wiley.com/doi/10.1111/1471-0528.12147/epdf


Davenport et. Al. publication pending.

Delgado G, Condly SJ, Davenport M, Tinnakornsrisuphap T, Mack J, Khauv V, Zhou PS. A case series detailing the successful reversal of the effects of mifepristone using progesterone. Issues Law Med. 2018 Spring;33(1):21-31. PMID: 30831017.

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